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EPD The Eukaryotic Promoter Database

  • Please use this form (or our forum Ask EPD) for questions and suggestions concerning the "Eukaryotic Promoter Database"
  • Questions sent to us will be made publicly searchable on our forum page
  • You can send an e-mail directly to our forum at [email protected]

Epd.epfl.ch   DA: 11 PA: 12 MOZ Rank: 23

EPD The Eukaryotic Promoter Database

  • EPD is a collection of eukaryotic promoters derived from published articles
  • Instead, the EPDnew databases (HT-EPD) are the result of merging EPD promoters whith in-house analysis of promoter-specific high-throughput data for selected organisms only
  • This process gives EPDnew high precision and …

Epd.epfl.ch   DA: 11 PA: 11 MOZ Rank: 23

EPD In 2020: Enhanced Data Visualization And Extension To

  • The Eukaryotic Promoter Database (EPD), available online at https://epd.epfl.ch, provides accurate transcription start site (TSS) information for promoters of 15 model organisms plus corresponding functional genomics data that can be viewed in a genome browser, queried or analyzed via web interfaces, or exported in standard formats (FASTA, BED, CSV) for …

Academic.oup.com   DA: 16 PA: 30 MOZ Rank: 48

FAIRsharing: Biodbcore-000653: EPD

  • The Eukaryotic Promoter Database (EPD) provides accurate transcription start site (TSS) information for promoters of 15 model organisms, from human to yeast to the malaria parasite Plasmodium falciparum
  • While the original database was a manually curated database based on published experiments, new promoter collections are now produced entirely

Fairsharing.org   DA: 15 PA: 19 MOZ Rank: 37

(PDF) The Eukaryotic Promoter Database (EPD)

  • The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 74

A Gene Therapy For Inherited Blindness Using DCas9-VPR

  • Catalytically inactive dCas9 fused to transcriptional activators (dCas9-VPR) enables activation of silent genes
  • Many disease genes have counterparts, which serve similar functions but are expressed in distinct cell types
  • One attractive option to compensate for the missing function of a defective gene could be to transcriptionally activate its functionally equivalent counterpart via dCas9-VPR.

Advances.sciencemag.org   DA: 23 PA: 27 MOZ Rank: 55

PPAR-gamma Induced AKT3 Expression Increases Levels Of

Prostate cancer (PC) is the most common cancer in adult males in the developed world and the second leading cause of cancer deaths [].It has …

Nature.com   DA: 14 PA: 28 MOZ Rank: 48

Overexpressed WDR3 Induces The Activation Of Hippo Pathway

  • WD repeat domain 3 (WDR3) is involved in a variety of cellular processes including gene regulation, cell cycle progression, signal transduction and apoptosis
  • However, the biological role of WDR3 in pancreatic cancer and the associated mechanism remains unclear
  • We seek to explore the immune-independent functions and relevant mechanism for WDR3 in pancreatic cancer.

Jeccr.biomedcentral.com   DA: 23 PA: 36 MOZ Rank: 66

IProEP: A Computational Predictor For Predicting Promoter

  • Promoter is a fundamental DNA element located around the transcription start site (TSS) and could regulate gene transcription
  • Promoter recognition is of great significance in determining transcription units, studying gene structure, analyzing gene regulation mechanisms, and annotating gene functional information
  • Many models have already been proposed to predict promoters.

Cell.com   DA: 12 PA: 50 MOZ Rank: 70

FAN1, A DNA Repair Nuclease, As A Modifier Of Repeat

  • Genome integrity is maintained by the concerted action of distinct DNA repair pathways
  • DNA nucleases resolve damaged DNA and unusual DNA structures that arise during cellular processes such as replication, recombination, and transcription.

Europepmc.org   DA: 13 PA: 23 MOZ Rank: 45

PPARɣ Drives IL-33-dependent ILC2 Pro-tumoral Functions

The promoter sequences (+100 bp up- and downstream flanking regions) of human or mouse IL-5 and IL-13 were obtained from the Eukaryotic Promoter Database (human genome version Dec 2013 GRCh38

Nature.com   DA: 14 PA: 28 MOZ Rank: 52

Transcriptional Control Of Chicken KLF7 Promoter In

  • Krüppel-like factor 7 (KLF7) has been reported to inhibit adipogenesis and regulate the development of the nervous system
  • However, transcription regulation of KLF7 remains poorly understood
  • In the current study, a 2196-bp-long 5′-flanking sequence of chicken KLF7 (−2286 bp to −91 bp, upstream of the translation start site) was studied for promoter activity, and there was a

Academic.oup.com   DA: 16 PA: 30 MOZ Rank: 57

Cancer-associated Fibroblasts-derived Exosomal MiR-17-5p

  • Colorectal cancer (CRC) is one of the most common cancers globally [], and metastasis is the leading cause of death.CRC metastasis is a multi-step, multi-stage, multi-gene process involving escape of cancer cells from the primary site, a lack of immune surveillance, and synergy of the tumour microenvironment (TME) [].Cancer-associated fibroblasts (CAFs) are the most …

Sciencedirect.com   DA: 21 PA: 38 MOZ Rank: 71

Proteomic Profiling Of The Neurons In Mice With Depressive

  • Chronic corticosterone (CORT) stress is an anxiety and depression inducing factor that involves the dysfunction of glucocorticoid receptor (GR), brain-derived neurotrophic factor (BDNF), and neuronal plasticity
  • However, the regulation of proteomic profiles in neurons suffering CORT stress is remaining elusive
  • Thus, the proteomic profiles of mouse neuronal C17.2 stem cells were

Molecularbrain.biomedcentral.com   DA: 32 PA: 35 MOZ Rank: 80

CENPE Promotes Lung Adenocarcinoma Proliferation And Is

  • 258 SHAN et al: FOXM1 REGULATES CENPE AND PROMOTES LUNG ADENOCARCINOMA PROLIFERATION with FA complementation group A, which may serve an important role in cell cycle control and the pathogenesis of tumor (14)
  • In summary, previous studies have demonstrated that

Spandidos-publications.com   DA: 30 PA: 31 MOZ Rank: 75

Cancers Free Full-Text Identification Of Cardiac

  • The eukaryotic translation initiation factor 4F complex (eIF4F) is a potential chemotherapeutic target in triple-negative breast cancer (TNBC)
  • This complex regulates cap-dependent translational initiation and consists of three core proteins: eIF4E, eIF4G, and eIF4A1
  • In this study, we focus on repositioning compounds as novel inhibitors of eIF4A1-mediated translation.

Mdpi.com   DA: 12 PA: 24 MOZ Rank: 51

Cell Cycle Exit During Bortezomib‐induced Osteogenic

  • Contribution: Conceptualization (equal), Funding acquisition (equal), Methodology (equal), Project administration (equal), Resources (equal), Supervision (equal), Writing - original draft (equal), Writing - review & editing (equal) Search for …

Onlinelibrary.wiley.com   DA: 23 PA: 23 MOZ Rank: 62

Yusuf Johari ORCID ID: 0000-0001-9933-5764 Accepted Article

  • determined based on the literature, Eukaryotic Promoter Database (EPD; epd.epfl.ch) or annotated 5’UTRs
  • Genomatix Gene Regulation software (MatInspector Release 8.2 and MatBase Version 9.4; Genomatix, Munich, Germany) was used to analyze the region ‒1000 to +200 relative to the TSS (or up to the start codon) to find putative

Onlinelibrary.wiley.com   DA: 23 PA: 27 MOZ Rank: 67

Hydroxycitric Acid Potentiates The Cytotoxic Effect Of

  • Hydroxycitric acid (HCA), a dietary-derived weight loss supplement, competitively inhibits ATP citrate lyase (ACLY)
  • Tamoxifen (TAM) is the most frequently used therapy for estrogen receptor (ER)-positive breast cancer patients, but its application was restricted due to efficacy related issues.

Sciencedirect.com   DA: 21 PA: 38 MOZ Rank: 77

How To Find Transcription Start Site In Promoter Analysis

  • The best annotation tool I've used is Ensembl's Biomart (link below)
  • If you have a list of gene names, go to Filter > Gene > Input external references ID list (Gene Name(s)).

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 89

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