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Ocriplasmin Ophthalmic Información Española De La Droga

  • Ocriplasmin se usa para tratar una condición del ojo llamada adhesión vitreomacular sintomática (sVMA, por sus siglas en inglés)
  • Como parte normal del envejecimiento, la sustancia similar al gel (vítreo) dentro del ojo se vuelve más líquida y comienza a alejarse de la retina, situada en la parte posterior del ojo.

Drugs.com   DA: 13 PA: 36 MOZ Rank: 49

Jetrea (ocriplasmin) Dose, Indications, Adverse

  • Instruct patients to report any symptoms suggestive of endophthalmitis or retinal detachment (e.g., eye pain, redness of the eye, photophobia, blurred or decreased vision) without delay
  • Repeated administration of ocriplasmin in the same eye is not recommended
  • Reconstitution (2.5 mg/mL vial corresponding to 0.5 mg):

Pdr.net   DA: 7 PA: 37 MOZ Rank: 45

Current And Potential Uses Of Ocriplasmin

  • The Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes study comprised two separate multicenter, randomized, double-blind clinical trials that treated 464 eyes with VMA with a single, 125 μg intravitreal injection of ocriplasmin (See Figure 1) and compared the results to 188 eyes that received a placebo injection.

Reviewofophthalmology.com   DA: 29 PA: 50 MOZ Rank: 81

Ocriplasmin For Treating Vitreomacular Traction

  • 7.7%, ocriplasmin 29.8%, p<0.001; total PVD: placebo 2.6%, ocriplasmin 17.0%, p<0.001)
  • Further secondary outcomes did not show a statistically significant difference between the treatment arms but did favour ocriplasmin (proportion of patients who received a vitrectomy by month 6: placebo 15.4%, ocriplasmin

Nice.org.uk   DA: 15 PA: 50 MOZ Rank: 68

Ocriplasmin Ophthalmic Uses, Side Effects & Warnings

  • Ocriplasmin is used to treat an eye condition called symptomatic vitreomacular adhesion (sVMA)
  • As a normal part of aging, the gel-like substance (vitreous) inside the eye becomes more liquid and begins to pull away from the retina, located at the back of the eye.

Drugs.com   DA: 13 PA: 32 MOZ Rank: 49

(PDF) Pharmacokinetics Of Ocriplasmin In Vitreous

Concentrations of active ocriplasmin in PBS ( A) or porcine vitreous fl uid ( B) [M] and data fits following the addition of 0, 50, 125, 175, and 250 l g ocriplasmin and incubation at 37 8 C

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 75

What Is Ocriplasmin

  • Ocriplasmin injection is used to treat symptomatic vitreomacular adhesion.Symptomatic vitreomacular adhesion is an eye condition related to aging that may lead to blurring of vision or blindness.
  • This medicine is only administered by or under the supervision of your doctor.

Goodrx.com   DA: 14 PA: 20 MOZ Rank: 40

Ocriplasmin Drug Information

Ocriplasmin(Jetrea) generic is a proteolytic enzyme, prescribed for symptomatic vitreomacular adhesion, a progressive visual condition.

Medindia.net   DA: 16 PA: 41 MOZ Rank: 64

Ocriplasmin: Indications, Side Effects, Warnings

  • Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products
  • This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment
  • Data sources include IBM Watson Micromedex (updated 11 Oct 2021), Cerner Multum™ (updated …

Drugs.com   DA: 13 PA: 21 MOZ Rank: 42

Ocriplasmin Research To Better Inform Treatment (ORBIT

  • Ocriplasmin Research to Better Inform Treatment (ORBIT) (ORBIT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators
  • Listing a study does not mean it has been evaluated by the U.S
  • Read our disclaimer for details
  • ClinicalTrials.gov Identifier: NCT02079883.

Clinicaltrials.gov   DA: 18 PA: 21 MOZ Rank: 48

Retinal Physician

  • Patient Selection for Ocriplasmin Treatment of Patients With VMT The honeymoon is over, but the marriage is stable
  • V ery few topics in the treatment of ophthalmic diseases have merited their being introduced in the New England Journal of Medicine
  • Ocriplasmin is a member of that elite group
  • 1 It is a novel and potentially …

Retinalphysician.com   DA: 24 PA: 50 MOZ Rank: 84

Italian Real-life Experience On The Use Of Ocriplasmin

  • ocriplasmin, a closure rate of 40.6% was found versus 10.6% in the placebo group
  • Ocriplasmin was then approved for the non-surgical treatment of symptomatic VMT associated or not to FTMH less than 400 micra.3 Since the real-world use of the drug began, there have been favourable reports of visual improvement after ocriplasmin injec-

Bmjophth.bmj.com   DA: 16 PA: 38 MOZ Rank: 65

Ocriplasmin Ophthalmic Cigna

  • Ocriplasmin is used to treat an eye condition called symptomatic vitreomacular adhesion (sVMA)
  • As a normal part of aging, the gel-like substance (vitreous) inside the eye becomes more liquid and begins to pull away from the retina, located at the back of the eye
  • This is called posterior vitreous detachment

Cigna.com   DA: 13 PA: 50 MOZ Rank: 75

Ocriplasmin (Jetrea) (125 Mcg Intravitreal Injection

  • Safety profile of ocriplasmin for the pharmacologic treatment of symptomatic vitreomacular adhesion/traction
  • Kaiser PK, Kampik A, Kuppermann BD, Girach A, Rizzo S, Sergott RC

Ncbi.nlm.nih.gov   DA: 20 PA: 17 MOZ Rank: 50

Ocriplasmin (Jetrea)

  • On October 18, 2012, the Food and Drug Administration (FDA) approved ocriplasmin (Jetrea) for the treatment of symptomatic VMA
  • The recommended dosage of ocriplasmin is 0.125 mg (0.1 ml of the diluted solution) administered by intra …

Aetna.com   DA: 13 PA: 35 MOZ Rank: 62

Ocriplasmin (PF) Intravitreal: Uses, Side Effects

Find patient medical information for ocriplasmin (PF) intravitreal on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Webmd.com   DA: 13 PA: 50 MOZ Rank: 78

Redesigning Services For The Management Of Vitreomacular

  • Success with ocriplasmin is expected in up to 50% of VMT patients with MH and up to 37.4% of VMT patients without MH (and without ERM)
  • 27, 45 A recently published series of 19 cases of patients

Nature.com   DA: 14 PA: 20 MOZ Rank: 50

(PDF) Cost-effectiveness Of Ocriplasmin For The Treatment

  • If intravitreal injection of ocriplasmin was the primary procedure, the overall imputed cost was $8767 to $10 977
  • The cost per line ranged from $3549 to …

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 87

Ocriplasmin Injection Linked To Impaired Vision

Ocriplasmin for the treatment of symptomatic vitreomacular adhesion (VMA) is linked to visual impairment, according to 2 case reports published online February 27 in JAMA Ophthalmology.One expert

Medscape.com   DA: 16 PA: 19 MOZ Rank: 53

Ocriplasmin Memorial Sloan Kettering Cancer Center

  • This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
  • Jetrea [DSC] Brand Names: Canada
  • Jetrea [DSC] What is this drug used for? It is used to treat vitreomacular adhesion (VMA).

Mskcc.org   DA: 13 PA: 42 MOZ Rank: 74

NHWorks Job Match

NHWorks Job Match by Looking for a job in New Hampshire? Want to find jobs that match your skill set or training through the convenience of your mobile device?

Nhworksjobmatch.nhes.nh.gov   DA: 27 PA: 19 MOZ Rank: 66

Retina Specialists Report Problems With Ocriplasmin

  • Ocriplasmin is a recombinant protease with activity against fibronectin and laminin
  • Soon after the injectable was approved by the US Food and Drug Administration (FDA) in October 2012, reports

Medscape.com   DA: 16 PA: 19 MOZ Rank: 56

Cost-effectiveness Of Ocriplasmin For The Treatment Of

  • Ocriplasmin treatment was associated with higher QALY gains and incremental costs in all three subgroups when compared to standard of care
  • Based on commonly accepted UK cost-effectiveness willingness-to-pay thresholds of £20,000 to £30,000 per QALY, the results seen in the VMT without either ERM or FTMH subgroup were considered highly cost

Europepmc.org   DA: 13 PA: 21 MOZ Rank: 56

Jetrea Drug Information PDR.net

The Related Drug Information Index provides comprehensive access to all drug information related to a specific drug Types of content include full prescribing information, drug summaries, Full Prescribing Information Continuing Medication Education (Full PI CME), Medication Guides, Risk Evaluation and Mitigation Strategies (REMS Summaries), REMS Continuing Medication …

Pdr.net   DA: 11 PA: 24 MOZ Rank: 58

Ocriplasmin Ophthalmic CS Mott Children's Hospital

  • Ocriplasmin is used to treat an eye condition called symptomatic vitreomacular adhesion (sVMA)
  • As a normal part of aging, the gel-like substance (vitreous) inside the eye becomes more liquid and begins to pull away from the retina, located at the back of the eye
  • This is called posterior vitreous detachment
  • sVMA occurs when small areas of the

Mottchildren.org   DA: 20 PA: 24 MOZ Rank: 68

(A) Cartoon Representation Of The Structure Of The

Ocriplasmin, a truncated form of plasmin, is commercialized in the USA and in Europe under the trade name Jetrea®, and indicated for the treatment …

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 95



Oclins.com   DA: 14 PA: 14 MOZ Rank: 54


  • is of a secondary endpoint from the OASIS trial
  • Patients received a single intravitreal injection of ocriplasmin (0.125 mg) or sham and completed the VFQ-25 questionnaire at baseline and at Months 6, 12, and 24
  • Clinically meaningful (≥5-point) changes from baseline were assessed
  • Results: Of the 220 patients enrolled, 146 received ocriplasmin and 74 received sham

Journals.lww.com   DA: 16 PA: 50 MOZ Rank: 93

Visual Function Response To Ocriplasmin For The Treatment

  • Ocriplasmin treatment resulted in a better response for all three measures, although the difference did not reach significance for the driving subscale
  • The proportion of ocriplasmin‐treated participants who responded to at least one of these visual function measures was 55.1%, significantly higher than the 34.2% seen in the placebo

Onlinelibrary.wiley.com   DA: 23 PA: 27 MOZ Rank: 78

Inactivation Of Ocriplasmin In PBS Is Due To Autolysis

Ocriplasmin (also known as des-kringle 1-5 plasmin or microplasmin) ( Table 2), a proteolytic enzyme and truncated form of human plasmin produced in …

Researchgate.net   DA: 20 PA: 50 MOZ Rank: 99

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